Attributes
UniProt ID
Protein Name
Nicotinamide phosphoribosyltransferase
Ligand Name
N-{4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-N'-[(pyridin-3-yl)methyl]urea
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KKBVILNJYCRNQY-UHFFFAOYSA-N
SMILES
c1ccc2c(c1)C(=O)N(C2=O)Cc3ccc(cc3)NC(=O)NCc4cccnc4
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6ATB
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Color Legend
Unassigned regionsLigand / hetero atomse6atbA1e6atbA2e6atbA3e6atbB1e6atbB2e6atbC1e6atbC2e6atbC3e6atbD1e6atbD2e6atbD3
ECOD domains from experimental PDB structures interacting with ligand BWA
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P43490 | n/a | BWA | 6atb | e6atbA1 | A:9-161,A:392-427 |
| P43490 | n/a | BWA | 6atb | e6atbA3 | A:162-391 |
| P43490 | n/a | BWA | 6atb | e6atbB1 | B:9-160 |
| P43490 | n/a | BWA | 6atb | e6atbB2 | B:161-487 |
| P43490 | n/a | BWA | 6atb | e6atbC1 | C:9-161,C:392-427 |
| P43490 | n/a | BWA | 6atb | e6atbC2 | C:162-391 |
| P43490 | n/a | BWA | 6atb | e6atbD2 | D:9-161,D:392-427 |
| P43490 | n/a | BWA | 6atb | e6atbD3 | D:162-391 |