(1S,2S)-N-{4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-(pyridin-3-yl)cyclopropane-1-carboxamide
P43490 — Nicotinamide phosphoribosyltransferase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand C5V
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand C5V
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P43490 | n/a | 6azj | C5V | A | 501 | e6azjA3 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |
| P43490 | n/a | 6azj | C5V | A | 501 | e6azjB3 | alpha/beta-Hammerhead/Barrel-sandwich hybrid | alpha/beta-Hammerhead/Barrel-sandwich hybrid | Nicotinate/Quinolinate PRTase N-terminal domain-like | NAPRTase,NAMPT_N |
| P43490 | n/a | 6azj | C5V | B | 501 | e6azjA2 | alpha/beta-Hammerhead/Barrel-sandwich hybrid | alpha/beta-Hammerhead/Barrel-sandwich hybrid | Nicotinate/Quinolinate PRTase N-terminal domain-like | NAPRTase,NAMPT_N |
| P43490 | n/a | 6azj | C5V | B | 501 | e6azjA3 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |
| P43490 | n/a | 6azj | C5V | B | 501 | e6azjB1 | TIM beta/alpha-barrel | TIM barrels | TIM barrels | NAPRTase |