DrugDomain logoDrugDomain

N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-4-[2-(1-methylethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]benzenesulfonamide

P45983 — Mitogen-activated protein kinase 8

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand AQ2

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand AQ2

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P45983n/a4awiAQ2A1365e4awiA1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase