6-[(7-methyl-2-propyl-imidazo[4,5-b]pyridin-4-yl)methyl]-2-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-1,3-benzothiazole

P48163 — NADP-dependent malic enzyme

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 86I

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 86I

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P48163	n/a	7x11	86I	A	603	e7x11A1	Flavodoxin-like	Class I glutamine amidotransferase-like	Aminoacid dehydrogenase-like, N-terminal domain	malic
P48163	n/a	7x11	86I	A	603	e7x11A2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Malic_M
P48163	n/a	7x11	86I	A	603	e7x11A3	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	Malic_M
P48163	n/a	7x11	86I	B	603	e7x11B1	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	Malic_M
P48163	n/a	7x11	86I	B	603	e7x11B2	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Malic_M
P48163	n/a	7x11	86I	B	603	e7x11B3	Flavodoxin-like	Class I glutamine amidotransferase-like	Aminoacid dehydrogenase-like, N-terminal domain	malic
P48163	n/a	7x11	86I	C	603	e7x11C1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Malic_M
P48163	n/a	7x11	86I	C	603	e7x11C2	Flavodoxin-like	Class I glutamine amidotransferase-like	Aminoacid dehydrogenase-like, N-terminal domain	malic
P48163	n/a	7x11	86I	C	603	e7x11C3	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	Malic_M
P48163	n/a	7x11	86I	D	603	e7x11D1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Malic_M
P48163	n/a	7x11	86I	D	603	e7x11D2	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	C-terminal domain of Malic enzyme	Malic_M
P48163	n/a	7x11	86I	D	603	e7x11D3	Flavodoxin-like	Class I glutamine amidotransferase-like	Aminoacid dehydrogenase-like, N-terminal domain	malic