Attributes
UniProt ID
Protein Name
Isocitrate dehydrogenase , mitochondrial -specific ICDH
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 4JA8
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Color Legend
Unassigned regionsLigand / hetero atomse4ja8A1e4ja8A2e4ja8B1e4ja8B2
ECOD domains from experimental PDB structures interacting with ligand DB02338
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P48735 | DB02338 | NDP | 4ja8 | e4ja8A1 | A:41-145,A:326-456 |
| P48735 | DB02338 | NDP | 4ja8 | e4ja8B1 | B:43-145,B:326-448 |
| P48735 | DB02338 | NDP | 5i95 | e5i95A1 | A:41-145,A:326-453 |
| P48735 | DB02338 | NDP | 5i95 | e5i95A2 | A:146-325 |
| P48735 | DB02338 | NDP | 5i96 | e5i96A1 | A:41-145,A:326-457 |
| P48735 | DB02338 | NDP | 5i96 | e5i96B2 | B:43-145,B:326-449 |
| P48735 | DB02338 | NDP | 5svn | e5svnA1 | A:146-325 |
| P48735 | DB02338 | NDP | 5svn | e5svnA2 | A:43-145,A:326-450 |
| P48735 | DB02338 | NDP | 5svn | e5svnB1 | B:146-325 |
| P48735 | DB02338 | NDP | 5svn | e5svnB2 | B:43-145,B:326-451 |
| P48735 | DB02338 | NDP | 6adi | e6adiA1 | A:41-145,A:326-458 |
| P48735 | DB02338 | NDP | 6adi | e6adiB1 | B:43-145,B:326-449 |
| P48735 | DB02338 | NDP | 6vfz | e6vfzA1 | A:41-145,A:326-456 |
| P48735 | DB02338 | NDP | 6vfz | e6vfzB1 | B:43-145,B:326-448 |