DrugDomain logoDrugDomain

Attributes

UniProt ID
P49137
Protein Name
MAP kinase-activated protein kinase 2
Ligand Name
2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE
DrugBank ID
DB08358
PDB Ligand Accession
P4O
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
OWFLADWRSCINST-UHFFFAOYSA-N
SMILES
c1ccc2c(c1)cc(cn2)c3cc(ccn3)c4cc5c([nH]4)CCNC5=O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 2JBO
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse2jboA1
ECOD domains from experimental PDB structures interacting with ligand DB08358
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P49137DB08358P4O2jboe2jboA1A:44-347
P49137DB08358P4O2jbpe2jbpA1A:46-350
P49137DB08358P4O2jbpe2jbpB1B:46-350
P49137DB08358P4O2jbpe2jbpC1C:46-350
P49137DB08358P4O2jbpe2jbpD1D:47-350
P49137DB08358P4O2jbpe2jbpE1E:44-345
P49137DB08358P4O2jbpe2jbpF1F:45-350
P49137DB08358P4O2jbpe2jbpG1G:45-350
P49137DB08358P4O2jbpe2jbpH1H:46-347
P49137DB08358P4O2jbpe2jbpI1I:45-350
P49137DB08358P4O2jbpe2jbpK1K:47-214,K:241-345
P49137DB08358P4O2jbpe2jbpL1L:44-215,L:240-345
P49137DB08358P4O3goke3gokA1A:46-350
P49137DB08358P4O3goke3gokB1B:46-350
P49137DB08358P4O3goke3gokC1C:46-350
P49137DB08358P4O3goke3gokD1D:46-350
P49137DB08358P4O3goke3gokE1E:46-350
P49137DB08358P4O3goke3gokF1F:46-350
P49137DB08358P4O3goke3gokG1G:46-350
P49137DB08358P4O3goke3gokH1H:46-350
P49137DB08358P4O3goke3gokI1I:46-350
P49137DB08358P4O3goke3gokJ1J:46-350
P49137DB08358P4O3goke3gokK1K:46-350
P49137DB08358P4O3goke3gokL1L:46-350
P49137DB08358P4O3r2ye3r2yA1A:46-215,A:241-345