PHOSPHATE ION

P49327 — Fatty acid synthase S-acetyltransferase ; S-malonyltransferase ; 3-oxoacyl- synthase ; 3-oxoacyl- reductase ; 3-hydroxyacyl- dehydratase ; Enoyl- reductase ; Acyl- hydrolase ]

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB14523

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P49327	DB14523	PO4	001316210	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
P49327	DB14523	PO4	001316212	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N

Show other predicted domains (74)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1XKT	e1xktA1	7579.1.1	alpha/beta-Hydrolases	alpha/beta-Hydrolases	alpha/beta-Hydrolases	COesterase
1XKT	e1xktB1	7579.1.1	alpha/beta-Hydrolases	alpha/beta-Hydrolases	alpha/beta-Hydrolases	COesterase
2JFD	e2jfdC5	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfdB5	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfdA5	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfdD5	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfdC3	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfdB3	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfdA3	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfdD3	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfdC4	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e2jfdB4	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e2jfdA4	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e2jfdD4	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
2JFK	e2jfkA1	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfkD5	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfkC5	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfkB5	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e2jfkA2	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfkD3	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfkC3	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfkB3	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e2jfkA3	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e2jfkD4	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e2jfkC4	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e2jfkB4	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
2PX6	e2px6A1	7579.1.1	alpha/beta-Hydrolases	alpha/beta-Hydrolases	alpha/beta-Hydrolases	COesterase
2PX6	e2px6B1	7579.1.1	alpha/beta-Hydrolases	alpha/beta-Hydrolases	alpha/beta-Hydrolases	COesterase
3HHD	e3hhdA1	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e3hhdD6	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e3hhdC6	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e3hhdB6	2007.1.19	Flavodoxin-like	Class I glutamine amidotransferase-like	FabD/lysophospholipase-like	Acyl_transf_1
	e3hhdA2	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e3hhdD8	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e3hhdC8	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e3hhdB8	304.11.1	Alpha-beta plaits	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Probable ACP-binding domain of malonyl-CoA ACP transacylase	Acyl_transf_1
	e3hhdA5	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e3hhdD5	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e3hhdC5	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e3hhdB5	6094.1.1	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KS-MAT linker domain in fatty acid synthase	KAsynt_C_assoc
	e3hhdA4	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
	e3hhdA3	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
	e3hhdD7	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
	e3hhdD9	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
	e3hhdC7	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
	e3hhdC9	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
	e3hhdB7	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
	e3hhdB9	7581.1.1	Thiolase-like	Thiolase-like	Thiolase-like	Thiolase_N
3TJM	e3tjmA1	7579.1.1	alpha/beta-Hydrolases	alpha/beta-Hydrolases	alpha/beta-Hydrolases	COesterase
4PIV	e4pivA1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4pivA2	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4pivB2	2003.1.5	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	DNA_methylase
	e4pivA3	2003.1.5	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	DNA_methylase
4W82	e4w82A1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4w82B1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4w82A2	236.1.1	GroES-like	GroES-related	Alcohol dehydrogenase-like, N-terminal domain	ADH_N
	e4w82B2	236.1.1	GroES-like	GroES-related	Alcohol dehydrogenase-like, N-terminal domain	ADH_N
4W9N	e4w9nA1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4w9nB1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4w9nD1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4w9nC1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e4w9nA2	236.1.1	GroES-like	GroES-related	Alcohol dehydrogenase-like, N-terminal domain	ADH_N
	e4w9nB2	236.1.1	GroES-like	GroES-related	Alcohol dehydrogenase-like, N-terminal domain	ADH_N
	e4w9nD2	236.1.1	GroES-like	GroES-related	Alcohol dehydrogenase-like, N-terminal domain	ADH_N
	e4w9nC2	236.1.1	GroES-like	GroES-related	Alcohol dehydrogenase-like, N-terminal domain	ADH_N
4Z49	e4z49A1	7579.1.1	alpha/beta-Hydrolases	alpha/beta-Hydrolases	alpha/beta-Hydrolases	COesterase
4Z49	e4z49B1	7579.1.1	alpha/beta-Hydrolases	alpha/beta-Hydrolases	alpha/beta-Hydrolases	COesterase
5C37	e5c37C1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e5c37C3	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e5c37C4	2003.1.5	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	DNA_methylase
6NNA	e6nnaA2	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e6nnaB1	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e6nnaB2	2003.1.1	Rossmann-like	Rossmann-related	NAD(P)-binding Rossmann-fold domains	Gp_dh_N
	e6nnaB3	2003.1.5	Rossmann-like	Rossmann-related	S-adenosyl-L-methionine-dependent methyltransferases	DNA_methylase

ECOD domains from experimental PDB structures interacting with ligand DB14523

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P49327	DB14523	2cg5	PO4	A	1303	e2cg5B1	ACP-like	Acyl-carrier protein (ACP)	Acyl-carrier protein (ACP)	PP-binding