tert-butyl 4-({(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)[(2-methylphenyl)sulfonyl]amino}methyl)piperidine-1-carboxylate

P49356 — Protein farnesyltransferase subunit beta

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand ED5

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P49356	None	ED5	000004484	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
P49356	None	ED5	000059444	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans

Show other predicted domains (11)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1JCQ	e1jcqB1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
1LD7	e1ld7B1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
1LD8	e1ld8B1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
1MZC	e1mzcB1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
1S63	e1s63B1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
1SA4	e1sa4B1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
1TN6	e1tn6B1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
2H6G	e2h6gB1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
2H6H	e2h6hB1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
2H6I	e2h6iB1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans
2IEJ	e2iejB1	109.2.1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans

ECOD domains from experimental PDB structures interacting with ligand ED5

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P49356	n/a	3e37	ED5	B	1	e3e37B1	Repetitive alpha hairpins	alpha/alpha toroid	alpha/alpha toroid	Prenyltrans