2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL

P49916 — DNA ligase 3

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03754

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P49916	DB03754	TRS	000177041	2.1.1	OB-fold	Nucleic acid-binding protein	Nucleic acid-binding protein	Ribosom_S12_S23
P49916	DB03754	TRS	001159100	206.1.3	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	ATP-grasp	DNA_ligase_A_M

Show other predicted domains (9)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1IMO	e1imoA1	7568.1.1	BRCT domain	BRCT domain	BRCT domain	BRCT
1IN1	e1in1A1	7568.1.1	BRCT domain	BRCT domain	BRCT domain	BRCT
1UW0	e1uw0A1	377.1.2	Glucocorticoid receptor-like	LIM domain-like	PARP-type zinc finger	zf-PARP
3L2P	e3l2pA9	4095.1.1	ATP-dependent DNA ligase DNA-binding domain	ATP-dependent DNA ligase DNA-binding domain	ATP-dependent DNA ligase DNA-binding domain	DNA_ligase_A_N
3L2P	e3l2pA10	4095.1.1	ATP-dependent DNA ligase DNA-binding domain	ATP-dependent DNA ligase DNA-binding domain	ATP-dependent DNA ligase DNA-binding domain	DNA_ligase_A_N
3PC7	e3pc7A1	7568.1.1	BRCT domain	BRCT domain	BRCT domain	BRCT
3PC7	e3pc7B1	7568.1.1	BRCT domain	BRCT domain	BRCT domain	BRCT
3QVG	e3qvgA1	7568.1.1	BRCT domain	BRCT domain	BRCT domain	BRCT
3QVG	e3qvgC1	7568.1.1	BRCT domain	BRCT domain	BRCT domain	BRCT

ECOD domains from experimental PDB structures interacting with ligand DB03754

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P49916	DB03754	3pc8	TRS	D	2	e3pc8D1	BRCT domain	BRCT domain	BRCT domain	LIG3_BRCT