Attributes
UniProt ID
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Ligand Name
2-methyl-3-{(3S)-1-[(1-pyridin-2-ylcyclopropyl)carbonyl]pyrrolidin-3-yl}-1H-pyrrolo[2,3-b]pyridine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
HUWRMRPEILCPLL-OAHLLOKOSA-N
SMILES
Cc1c(c2cccnc2[nH]1)C3CCN(C3)C(=O)C4(CC4)c5ccccn5
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 3GMD
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Color Legend
Unassigned regionsLigand / hetero atomse3gmdA1e3gmdB1e3gmdC1e3gmdD1e3gmdE1e3gmdF1e3gmdG1e3gmdH1
ECOD domains from experimental PDB structures interacting with ligand 2M3
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P50172 | n/a | 2M3 | 3gmd | e3gmdA1 | A:26-289 |
| P50172 | n/a | 2M3 | 3gmd | e3gmdB1 | B:26-289 |
| P50172 | n/a | 2M3 | 3gmd | e3gmdC1 | C:26-289 |
| P50172 | n/a | 2M3 | 3gmd | e3gmdD1 | D:26-289 |
| P50172 | n/a | 2M3 | 3gmd | e3gmdE1 | E:26-289 |
| P50172 | n/a | 2M3 | 3gmd | e3gmdF1 | F:26-289 |
| P50172 | n/a | 2M3 | 3gmd | e3gmdG1 | G:26-289 |
| P50172 | n/a | 2M3 | 3gmd | e3gmdH1 | H:26-289 |