DrugDomain logoDrugDomain

Attributes

UniProt ID
P50172
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Ligand Name
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
DrugBank ID
DB02338
PDB Ligand Accession
NDP
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
ACFIXJIJDZMPPO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)OP(=O)(O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Mol*
Structure: 1Y5M
Open File
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse1y5mA1e1y5mB1
ECOD domains from experimental PDB structures interacting with ligand DB02338
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P50172DB02338NDP1y5me1y5mA1A:25-289
P50172DB02338NDP1y5me1y5mB1B:25-289
P50172DB02338NDP1y5re1y5rA1A:25-289
P50172DB02338NDP1y5re1y5rB1B:25-289
P50172DB02338NDP3gmde3gmdA1A:26-289
P50172DB02338NDP3gmde3gmdB1B:26-289
P50172DB02338NDP3gmde3gmdC1C:26-289
P50172DB02338NDP3gmde3gmdD1D:26-289
P50172DB02338NDP3gmde3gmdE1E:26-289
P50172DB02338NDP3gmde3gmdF1F:26-289
P50172DB02338NDP3gmde3gmdG1G:26-289
P50172DB02338NDP3gmde3gmdH1H:26-289
P50172DB02338NDP4k26e4k26A1A:25-289
P50172DB02338NDP4k26e4k26B1B:25-289
P50172DB02338NDP4nmhe4nmhA1A:25-289
P50172DB02338NDP4nmhe4nmhB1B:26-289
P50172DB02338NDP4nmhe4nmhC1C:25-289
P50172DB02338NDP4nmhe4nmhD1D:26-289