Attributes
UniProt ID
Protein Name
Isocitrate dehydrogenase subunit alpha, mitochondrial -specific ICDH subunit alpha
Ligand Name
NICOTINAMIDE-ADENINE-DINUCLEOTIDE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BAWFJGJZGIEFAR-NNYOXOHSSA-N
SMILES
c1cc(c[n+](c1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4ncnc5N)O)O)O)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6KDY
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Color Legend
Unassigned regionsLigand / hetero atomse6kdyA1e6kdyA2e6kdyB1e6kdyB2e6kdyC1e6kdyC2e6kdyD1e6kdyD2e6kdyE1e6kdyE2e6kdyF1e6kdyF2e6kdyG1e6kdyG2e6kdyH1e6kdyH2
ECOD domains from experimental PDB structures interacting with ligand DB14128
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P50213 | DB14128 | NAD | 6kdy | e6kdyA2 | A:3-94,A:242-337 |
| P50213 | DB14128 | NAD | 6kdy | e6kdyC1 | C:3-94,C:242-337 |
| P50213 | DB14128 | NAD | 6kdy | e6kdyE1 | E:4-94,E:242-337 |
| P50213 | DB14128 | NAD | 6kdy | e6kdyE2 | E:95-241 |
| P50213 | DB14128 | NAD | 6kdy | e6kdyG2 | G:3-94,G:242-337 |
| P50213 | DB14128 | NAD | 8gru | e8gruA1 | A:3-94,A:242-337 |
| P50213 | DB14128 | NAD | 8gru | e8gruA2 | A:95-241 |
| P50213 | DB14128 | NAD | 8gru | e8gruC1 | C:95-241 |
| P50213 | DB14128 | NAD | 8gru | e8gruC2 | C:3-94,C:242-337 |