Attributes
UniProt ID
Protein Name
Isocitrate dehydrogenase subunit alpha, mitochondrial -specific ICDH subunit alpha
Ligand Name
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BOPGDPNILDQYTO-NNYOXOHSSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=CCC(=C5)C(=O)N)O)O)O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 5YVT
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse5yvtA1e5yvtA2e5yvtB1e5yvtB2
ECOD domains from experimental PDB structures interacting with ligand DB00157
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| P50213 | DB00157 | NAI | 5yvt | e5yvtA1 | A:4-94,A:242-337 |
| P50213 | DB00157 | NAI | 5yvt | e5yvtA2 | A:95-241 |
| P50213 | DB00157 | NAI | 6ke3 | e6ke3A2 | A:3-94,A:242-337 |
| P50213 | DB00157 | NAI | 6ke3 | e6ke3C1 | C:3-94,C:242-337 |
| P50213 | DB00157 | NAI | 6ke3 | e6ke3E1 | E:95-241 |
| P50213 | DB00157 | NAI | 6ke3 | e6ke3E2 | E:6-94,E:242-337 |
| P50213 | DB00157 | NAI | 6ke3 | e6ke3G1 | G:4-94,G:242-337 |