N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE

P51692 — Signal transducer and activator of transcription 5B

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB01254

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P51692	DB01254	1N1	nD4	108.1.1	EF-hand	EF-hand-related	EF-hand	STAT_linker
P51692	DB01254	1N1	nD5	214.1.1	SH2	SH2	SH2	SH2

Show other predicted domains (16)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
6MBW	e6mbwA3	108.1.1	EF-hand	EF-hand-related	EF-hand	EF-hand_1
	e6mbwB1	108.1.1	EF-hand	EF-hand-related	EF-hand	EF-hand_1
	e6mbwA2	11.1.5	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Common fold of diphtheria toxin/transcription factors/cytochrome f	Fimbrial
	e6mbwB4	11.1.5	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Common fold of diphtheria toxin/transcription factors/cytochrome f	Fimbrial
	e6mbwA1	214.1.1	SH2	SH2	SH2	SH2
	e6mbwB2	214.1.1	SH2	SH2	SH2	SH2
	e6mbwA4	603.2.1	STAT-like	STAT	STAT	STAT_alpha
	e6mbwB3	603.2.1	STAT-like	STAT	STAT	STAT_alpha
6MBZ	e6mbzA2	108.1.1	EF-hand	EF-hand-related	EF-hand	EF-hand_1
	e6mbzB1	108.1.1	EF-hand	EF-hand-related	EF-hand	EF-hand_1
	e6mbzA4	11.1.5	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Common fold of diphtheria toxin/transcription factors/cytochrome f	Fimbrial
	e6mbzB3	11.1.5	Immunoglobulin-like beta-sandwich	Immunoglobulin-related	Common fold of diphtheria toxin/transcription factors/cytochrome f	Fimbrial
	e6mbzA1	214.1.1	SH2	SH2	SH2	SH2
	e6mbzB4	214.1.1	SH2	SH2	SH2	SH2
	e6mbzA3	603.2.1	STAT-like	STAT	STAT	STAT_alpha
	e6mbzB2	603.2.1	STAT-like	STAT	STAT	STAT_alpha

ECOD domains from experimental PDB structures interacting with ligand DB01254

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found