DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Tyrosine-protein kinase JAK3
Ligand Name
(~{Z})-2-cyano-~{N},~{N}-dimethyl-3-[5-[3-[(1~{S},2~{R})-2-methylcyclohexyl]-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl]furan-2-yl]prop-2-enamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LVVYJCDRPPCFEQ-YXEVWGHGSA-N
SMILES
CC1CCCCC1n2c3c4cc[nH]c4ncc3nc2c5ccc(o5)C=C(C#N)C(=O)N(C)C
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 5LWN
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Color Legend
Unassigned regionsLigand / hetero atomse5lwnA1
ECOD domains from experimental PDB structures interacting with ligand 79R
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P52333n/a79R5lwne5lwnA1A:814-1103