(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE

P53350 — Serine/threonine-protein kinase PLK1

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB08059

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
P53350	DB08059	KWT	nD1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase, Pkinase_fungal
P53350	DB08059	KWT	nD2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box

Show other predicted domains (143)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
1Q4K	e1q4kA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4kC1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4kB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4kA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4kC2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4kB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
1Q4O	e1q4oB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4oA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4oB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1q4oA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
1UMW	e1umwA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1umwB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1umwA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e1umwB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
2OJX	e2ojxA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
2OJX	e2ojxA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
2OU7	e2ou7A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2OWB	e2owbA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2RKU	e2rkuA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2V5Q	e2v5qA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2V5Q	e2v5qB1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
2YAC	e2yacA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3BZI	e3bziA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3BZI	e3bziA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3C5L	e3c5lA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3C5L	e3c5lA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3FC2	e3fc2A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3FVH	e3fvhA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3FVH	e3fvhA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3HIH	e3hihA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3hihA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3hihB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3hihB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3HIK	e3hikA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3HIK	e3hikA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3KB7	e3kb7A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
3P2W	e3p2wA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P2W	e3p2wA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P2Z	e3p2zA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P2Z	e3p2zA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P34	e3p34A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P34	e3p34A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P35	e3p35A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p35A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p35B1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p35B2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p35C1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p35C2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P36	e3p36A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P36	e3p36A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3P37	e3p37A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p37A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p37B1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p37B2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p37C1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e3p37C2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3Q1I	e3q1iA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3Q1I	e3q1iA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3RQ7	e3rq7A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3RQ7	e3rq7A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
3THB	e3thbA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4A4L	e4a4lA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4A4O	e4a4oA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4DFW	e4dfwA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4DFW	e4dfwA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4E67	e4e67A3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4E67	e4e67A4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4E9C	e4e9cA3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4E9C	e4e9cA4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4E9D	e4e9dA3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4E9D	e4e9dA4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4H5X	e4h5xB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4h5xB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4h5xA3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4h5xA4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4H71	e4h71B1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4h71B2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4h71A3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4h71A4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4HAB	e4habA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4habA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4habB3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4habB4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4habC3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4habC4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4HCO	e4hcoB1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4hcoB2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4hcoA3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4hcoA4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4HY2	e4hy2A3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4HY2	e4hy2A4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4J52	e4j52A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4J53	e4j53A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
4LKL	e4lklA3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4LKL	e4lklA4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4LKM	e4lkmA3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4lkmA4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4lkmC3	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e4lkmC4	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4O56	e4o56A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4O56	e4o56A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4O6W	e4o6wA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4O6W	e4o6wA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4O9W	e4o9wA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4O9W	e4o9wA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4RCP	e4rcpA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4RCP	e4rcpA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4WHH	e4whhA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4WHH	e4whhA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4WHK	e4whkA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4WHK	e4whkA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4WHL	e4whlA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4WHL	e4whlA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4X9R	e4x9rA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4X9R	e4x9rA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4X9V	e4x9vA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4X9V	e4x9vA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4X9W	e4x9wA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
4X9W	e4x9wA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5J19	e5j19A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5j19A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5j19B1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e5j19B2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NEI	e5neiA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NEI	e5neiA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NFU	e5nfuA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NFU	e5nfuA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NJE	e5njeA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NJE	e5njeA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NMM	e5nmmA1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NMM	e5nmmA2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NN1	e5nn1A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NN1	e5nn1A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NN2	e5nn2A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5NN2	e5nn2A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
5TA6	e5ta6A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
5TA8	e5ta8A1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
6AX4	e6ax4A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
6AX4	e6ax4A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
6GY2	e6gy2A1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6gy2A2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6gy2B1	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box
	e6gy2B2	292.2.1	RIP/Polo-box domain	Polo-box domain	Polo-box domain	POLO_box

ECOD domains from experimental PDB structures interacting with ligand DB08059

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found