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Attributes

UniProt ID
Protein Name
Serine/threonine-protein kinase PLK1
Ligand Name
1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KNTGXMNWVXZIMW-UHFFFAOYSA-N
SMILES
Cc1cc(c(o1)C(F)(F)F)NC(=O)N=C2NC=C(S2)CCNc3cc(ncn3)Nc4nc[nH]n4
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: P53350_F1
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Color Legend
Unassigned regionsLigand / hetero atomsnD1nD2
ECOD domains from AlphaFold model interacting with ligand DB07789
UniProtDrugBankPDB LigandECOD DomainRange Definition
P53350DB07789FRSnD141-330
P53350DB07789FRSnD2371-600