(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE

P53350 — Serine/threonine-protein kinase PLK1

Attributes

UniProt ID

Protein Name

Serine/threonine-protein kinase PLK1

Ligand Name

(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

QDLHCMPXEPAAMD-QAIWCSMKSA-N

SMILES

CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(c5c(coc5C3=O)C(=O)OC4COC)C)C

Drug Action

n/a

Affinity Metrics

ki:1500 nM

ic50:5.8 nM