DrugDomain logoDrugDomain

(3R,4R,5S)-3-(3-chlorophenyl)-4-(4-chlorophenyl)-4-cyano-N-[(3S)-3,4-dihydroxybutyl]-5-(2,2-dimethylpropyl)-D-prolinamide

P56273 — E3 ubiquitin-protein ligase Mdm2

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand I09

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand I09

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P56273n/a4jrgI09A201e4jrgA1SWIB/MDM2 domainSWIB/MDM2 domainSWIB/MDM2 domainSWIB
P56273n/a4jrgI09B201e4jrgB1SWIB/MDM2 domainSWIB/MDM2 domainSWIB/MDM2 domainSWIB