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Kirill.Medvedev@ucf.edu
4-{[(5R,7S)-1-(3-fluorophenyl)-3,7-dimethyl-2,2-dioxido-2-thia-1,3,8-triazaspiro[4.5]dec-8-yl]methyl}-2-(propan-2-yloxy)phenol
P56817
— Beta-secretase 1
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ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand
0UP
UniProt
DrugBank
PDB Ligand
Domain Label
ECOD ID
X Group
H Group
T Group
F Group
No predicted ECOD data found
ECOD domains from experimental PDB structures interacting with ligand
0UP
UniProt
DrugBank
PDB ID
Ligand Acc.
Chain
Res No.
Exp. Domain
X Group
H Group
T Group
F Group
P56817
n/a
4fm7
0UP
A
501
e4fm7A2
cradle loop barrel
RIFT-related
acid protease
Asp
P56817
n/a
4fm7
0UP
A
501
e4fm7A3
cradle loop barrel
RIFT-related
acid protease
Asp
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