DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
(2Z,6S)-6-{3-chloro-5-[5-(prop-1-yn-1-yl)pyridin-3-yl]thiophen-2-yl}-2-imino-3,6-dimethyltetrahydropyrimidin-4(1H)-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
IJYPXSRDUPWKPB-SFHVURJKSA-N
SMILES
CC#Cc1cc(cnc1)c2cc(c(s2)C3(CC(=O)N(C(=N)N3)C)C)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4FRS
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Color Legend
Unassigned regionsLigand / hetero atomse4frsA2e4frsA3e4frsB2e4frsB3
ECOD domains from experimental PDB structures interacting with ligand 0V6
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/a0V64frse4frsA2A:245-446
P56817n/a0V64frse4frsA3A:58-244
P56817n/a0V64frse4frsB2B:245-446
P56817n/a0V64frse4frsB3B:57-244