DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
3-{5-[(2E,4S)-2-imino-1,4-dimethyl-6-oxohexahydropyrimidin-4-yl]thiophen-3-yl}benzonitrile
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
MLNWGLXMDFUREO-KRWDZBQOSA-N
SMILES
CC1(CC(=O)N(C(=N)N1)C)c2cc(cs2)c3cccc(c3)C#N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4HA5
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Color Legend
Unassigned regionsLigand / hetero atomse4ha5A2e4ha5A3e4ha5B2e4ha5B3
ECOD domains from experimental PDB structures interacting with ligand 13W
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/a13W4ha5e4ha5A2A:245-447
P56817n/a13W4ha5e4ha5A3A:58-244
P56817n/a13W4ha5e4ha5B2B:245-446
P56817n/a13W4ha5e4ha5B3B:58-244