DrugDomain logoDrugDomain

N-{3-[(4R,5R,6S)-2-amino-5-fluoro-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide

P56817 — Beta-secretase 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 1HG

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 1HG

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P56817n/a4j1k1HGA504e4j1kA2cradle loop barrelRIFT-relatedacid proteaseAsp
P56817n/a4j1k1HGA504e4j1kA3cradle loop barrelRIFT-relatedacid proteaseAsp