DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N-[(1S,2R)-3-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
RJXIEHBFRZLGTH-IZZNHLLZSA-N
SMILES
CC(=O)NC(Cc1cc(cc(c1)F)F)C(CNC2(CCCCC2)c3cccc(c3)C(C)(C)C)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 3IVH
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Color Legend
Unassigned regionsLigand / hetero atomse3ivhA2e3ivhA3
ECOD domains from experimental PDB structures interacting with ligand 1LI
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/a1LI3ivhe3ivhA2A:245-447
P56817n/a1LI3ivhe3ivhA3A:59-244