DrugDomain logoDrugDomain

3-[(4R)-2'-amino-1',2,2-trimethyl-5'-oxo-1',2,3,5'-tetrahydrospiro[chromene-4,4'-imidazol]-6-yl]benzonitrile

P56817 — Beta-secretase 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 1M6

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 1M6

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P56817n/a4jpc1M6A502e4jpcA2cradle loop barrelRIFT-relatedacid proteaseAsp
P56817n/a4jpc1M6A502e4jpcA3cradle loop barrelRIFT-relatedacid proteaseAsp