1-cyclopentyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-{[3-(trifluoromethyl)benzyl]amino}butan-2-yl]-6-oxo-5-(2-oxopyrrolidin-1-yl)-1,6-dihydropyridine-3-carboxamide
P56817 — Beta-secretase 1
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 1QU
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 1QU
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P56817 | n/a | 4k9h | 1QU | A | 401 | e4k9hA2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 4k9h | 1QU | A | 401 | e4k9hA3 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 4k9h | 1QU | B | 401 | e4k9hB2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 4k9h | 1QU | B | 401 | e4k9hB3 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 4k9h | 1QU | C | 401 | e4k9hC2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 4k9h | 1QU | C | 401 | e4k9hC3 | cradle loop barrel | RIFT-related | acid protease | Asp |