DrugDomain logoDrugDomain

(4R,4a'S,10a'S)-2-amino-8'-(2-fluoropyridin-3-yl)-1-methyl-3',4',4a',10a'-tetrahydro-1'H-spiro[imidazole-4,10'-pyrano[4,3-b]chromen]-5(1H)-one

P56817 — Beta-secretase 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 2EX

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 2EX

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P56817n/a4n002EXA502e4n00A1cradle loop barrelRIFT-relatedacid proteaseAsp
P56817n/a4n002EXA502e4n00A2cradle loop barrelRIFT-relatedacid proteaseAsp