(3S,4S,5R)-3-(3-bromo-4-hydroxybenzyl)-5-[(3-cyclopropylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide
P56817 — Beta-secretase 1
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 3P5
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 3P5
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P56817 | n/a | 3pi5 | 3P5 | A | 387 | e3pi5A2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 3pi5 | 3P5 | A | 387 | e3pi5A3 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 3pi5 | 3P5 | B | 387 | e3pi5B2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 3pi5 | 3P5 | B | 387 | e3pi5B3 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 3pi5 | 3P5 | C | 387 | e3pi5C2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 3pi5 | 3P5 | C | 387 | e3pi5C3 | cradle loop barrel | RIFT-related | acid protease | Asp |