DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N-{3-[(4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide
DrugBank ID
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
NIDRNVHMMDAAIK-YPMLDQLKSA-N
SMILES
c1cc(c(cc1NC(=O)c2ccc(cn2)F)C34COCC3CSC(=N4)N)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4X7I
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Color Legend
Unassigned regionsLigand / hetero atomse4x7iA1e4x7iA2e4x7iB1e4x7iB2
ECOD domains from experimental PDB structures interacting with ligand DB12547
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817DB125473YS4x7ie4x7iA1A:184-385
P56817DB125473YS4x7ie4x7iA2A:-4-183
P56817DB125473YS4x7ie4x7iB1B:184-385
P56817DB125473YS4x7ie4x7iB2B:-3-183