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Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N-[(4aS,6S,8aR)-2-amino-5,6,7,8-tetrahydro-4a,8a-(methanooxymethano)-3,1-benzothiazin-6(4H)-yl]-3-chlorobenzamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XDMHBNONUZHFDP-JQFCIGGWSA-N
SMILES
c1cc(cc(c1)Cl)C(=O)NC2CCC34COCC3(C2)CSC(=N4)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 4ZSR
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Color Legend
Unassigned regionsLigand / hetero atomse4zsrA1e4zsrA2e4zsrB1e4zsrB2
ECOD domains from experimental PDB structures interacting with ligand 4RY
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/a4RY4zsre4zsrA1A:184-385
P56817n/a4RY4zsre4zsrA2A:-4-183
P56817n/a4RY4zsre4zsrB1B:178-385
P56817n/a4RY4zsre4zsrB2B:-3-177