N-[(2S,3R)-3-hydroxy-4-({(2S,3S)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
P56817 — Beta-secretase 1
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand 5E7
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand 5E7
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P56817 | n/a | 5dqc | 5E7 | A | 401 | e5dqcA1 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 5dqc | 5E7 | A | 401 | e5dqcA2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 5dqc | 5E7 | B | 401 | e5dqcB1 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 5dqc | 5E7 | B | 401 | e5dqcB2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 5dqc | 5E7 | C | 401 | e5dqcC1 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 5dqc | 5E7 | C | 401 | e5dqcC2 | cradle loop barrel | RIFT-related | acid protease | Asp |