DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
(4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
UWUREBMKVJWTPP-PXNSSMCTSA-N
SMILES
Cc1c(c(on1)C)C2CC(N=C(S2)N)(C)c3cc(c(cc3F)F)c4cncnc4
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5ENK
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Color Legend
Unassigned regionsLigand / hetero atomse5enkA1e5enkA2
ECOD domains from experimental PDB structures interacting with ligand 5QV
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/a5QV5enke5enkA1A:47-231
P56817n/a5QV5enke5enkA2A:232-433