DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N-(6-{2-[2-(2-amino-3-{3-[(3,3-dimethylbutyl)amino]-3-oxopropyl}quinolin-6-yl)phenyl]ethyl}pyridin-3-yl)-4-fluorobenzamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
RTOUKFMBOVMEOT-UHFFFAOYSA-N
SMILES
CC(C)(C)CCNC(=O)CCc1cc2cc(ccc2nc1N)c3ccccc3CCc4ccc(cn4)NC(=O)c5ccc(cc5)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5I3Y
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Color Legend
Unassigned regionsLigand / hetero atomse5i3yA1e5i3yA2
ECOD domains from experimental PDB structures interacting with ligand 68K
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/a68K5i3ye5i3yA1A:184-385
P56817n/a68K5i3ye5i3yA2A:-1-183