DrugDomain logoDrugDomain

(1S)-4-fluoro-1-(4-fluoro-3-pyrimidin-5-ylphenyl)-1-[2-(trifluoromethyl)pyridin-4-yl]-1H-isoindol-3-amine

P56817 — Beta-secretase 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 7F3

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 7F3

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P56817n/a4azy7F3A1507e4azyA2cradle loop barrelRIFT-relatedacid proteaseAsp