DrugDomain logoDrugDomain

N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(trifluoromethyl)benzyl]amino}propyl]-3-(1,1-dioxido-1,2-thiazinan-2-yl)-5-(ethylamino)benzamide

P56817 — Beta-secretase 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand CM8

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand CM8

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P56817n/a2vnmCM8A2001e2vnmA3cradle loop barrelRIFT-relatedacid proteaseAsp