DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N'-[(1S,2R)-2-[(2R,4R)-4-(BENZYLOXY)PYRROLIDIN-2-YL]-1-(3,5-DIFLUOROBENZYL)-2-HYDROXYETHYL]-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
GZHSLBYVXGDJDF-NXVJRICRSA-N
SMILES
CCCN(CCC)C(=O)c1cc(cc(c1)C(=O)NC(Cc2cc(cc(c2)F)F)C(C3CC(CN3)OCc4ccccc4)O)C
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 2QMD
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Color Legend
Unassigned regionsLigand / hetero atomse2qmdA2e2qmdA3e2qmdB2e2qmdB3
ECOD domains from experimental PDB structures interacting with ligand CS7
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/aCS72qmde2qmdA2A:245-447
P56817n/aCS72qmde2qmdA3A:58-244
P56817n/aCS72qmde2qmdB2B:245-446
P56817n/aCS72qmde2qmdB3B:58-244