DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N-[(1S,2S)-1-[(3R,6R)-6-(cyclohexylmethoxy)morpholin-3-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XQHQHHREHKYCIG-CBPXPLCBSA-N
SMILES
CC(=O)NC(Cc1cc(cc(c1)F)F)C(C2COC(CN2)OCC3CCCCC3)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6BFW
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Color Legend
Unassigned regionsLigand / hetero atomse6bfwA1e6bfwA2e6bfwB1e6bfwB2
ECOD domains from experimental PDB structures interacting with ligand DK7
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/aDK76bfwe6bfwA1A:184-385
P56817n/aDK76bfwe6bfwA2A:-7-183
P56817n/aDK76bfwe6bfwB1B:-1-183
P56817n/aDK76bfwe6bfwB2B:184-385