DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
(10R,12S)-12-[(1R)-1,2-dihydroxyethyl]-N,N,10-trimethyl-14-oxo-2-oxa-13-azabicyclo[13.3.1]nonadeca-1(19),15,17-triene-17-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
FIDGRIKGIUHGAW-CZAAIQMYSA-N
SMILES
CC1CCCCCCCOc2cc(cc(c2)C(=O)N(C)C)C(=O)NC(C1)C(CO)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5QDD
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Color Legend
Unassigned regionsLigand / hetero atomse5qddA1e5qddA2e5qddB1e5qddB2e5qddC1e5qddC2
ECOD domains from experimental PDB structures interacting with ligand E7A
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/aE7A5qdde5qddA1A:-2-183
P56817n/aE7A5qdde5qddA2A:184-385
P56817n/aE7A5qdde5qddB1B:-2-183
P56817n/aE7A5qdde5qddB2B:184-385
P56817n/aE7A5qdde5qddC1C:184-385
P56817n/aE7A5qdde5qddC2C:-2-183