DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
(3S)-3-hydroxy-N-(2-methylpropyl)-N~2~-{[(4S)-17-[(methylsulfonyl)(propyl)amino]-2-oxo-3-azatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaen-4-yl]methyl}-L-norleucinamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
BUVUUWHTEARFCT-GOBOWQCMSA-N
SMILES
CCCC(C(C(=O)NCC(C)C)NCC1Cc2cccc(c2)CCCCc3cc(cc(c3)N(CCC)S(=O)(=O)C)C(=O)N1)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 6NV9
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Color Legend
Unassigned regionsLigand / hetero atomse6nv9A1e6nv9A2e6nv9B1e6nv9B2e6nv9C1e6nv9C2
ECOD domains from experimental PDB structures interacting with ligand L3M
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/aL3M6nv9e6nv9A1A:184-385
P56817n/aL3M6nv9e6nv9A2A:-2-183
P56817n/aL3M6nv9e6nv9B1B:184-386
P56817n/aL3M6nv9e6nv9B2B:-1-183
P56817n/aL3M6nv9e6nv9C1C:184-385
P56817n/aL3M6nv9e6nv9C2C:-1-183