DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N~3~-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-N~1~,N~1~-DIPROPYLBENZENE-1,3,5-TRICARBOXAMIDE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
XIQAKRFMIYGAIR-XZWHSSHBSA-N
SMILES
CCCN(CCC)C(=O)c1cc(cc(c1)C(=O)NC(Cc2cc(cc(c2)F)F)C(CNCc3cccc(c3)OC)O)C(=O)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 2P83
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse2p83A2e2p83A3e2p83B2e2p83B3e2p83C2e2p83C3
ECOD domains from experimental PDB structures interacting with ligand MR0
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/aMR02p83e2p83A2A:184-385
P56817n/aMR02p83e2p83A3A:61P-183
P56817n/aMR02p83e2p83B2B:184-386
P56817n/aMR02p83e2p83B3B:61P-183
P56817n/aMR02p83e2p83C2C:184-386
P56817n/aMR02p83e2p83C3C:61P-183