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Kirill.Medvedev@ucf.edu
(4S)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine
P56817
— Beta-secretase 1
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ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand
P6U
UniProt
DrugBank
PDB Ligand
Domain Label
ECOD ID
X Group
H Group
T Group
F Group
No predicted ECOD data found
ECOD domains from experimental PDB structures interacting with ligand
P6U
UniProt
DrugBank
PDB ID
Ligand Acc.
Chain
Res No.
Exp. Domain
X Group
H Group
T Group
F Group
P56817
n/a
5t1u
P6U
A
401
e5t1uA1
cradle loop barrel
RIFT-related
acid protease
Asp
P56817
n/a
5t1u
P6U
A
401
e5t1uA2
cradle loop barrel
RIFT-related
acid protease
Asp
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