N-{(1R,2R)-2-[(4aS,7aR)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]cyclopropyl}-5-fluoropyridine-2-carboxamide
P56817 — Beta-secretase 1
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand QJM
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand QJM
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P56817 | n/a | 6uvp | QJM | A | 402 | e6uvpA2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 6uvp | QJM | A | 402 | e6uvpB2 | cradle loop barrel | RIFT-related | acid protease | Asp |
| P56817 | n/a | 6uvp | QJM | B | 404 | e6uvpB1 | cradle loop barrel | RIFT-related | acid protease | Asp |