DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-[(2R,4R)-4-PHENOXYPYRROLIDIN-2-YL]ETHYL}-3-{[(2R)-2-(METHOXYMETHYL)PYRROLIDIN-1-YL]CARBONYL}-5-METHYLBENZAMIDE
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KYHYNSQLYDXSNK-MXWGZHRFSA-N
SMILES
Cc1cc(cc(c1)C(=O)N2CCCC2COC)C(=O)NC(Cc3cc(cc(c3)F)F)C(C4CC(CN4)Oc5ccccc5)O
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 2QMG
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Color Legend
Unassigned regionsLigand / hetero atomse2qmgA2e2qmgA3e2qmgB2e2qmgB3
ECOD domains from experimental PDB structures interacting with ligand SC6
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/aSC62qmge2qmgA2A:245-447
P56817n/aSC62qmge2qmgA3A:58-244
P56817n/aSC62qmge2qmgB2B:245-446
P56817n/aSC62qmge2qmgB3B:58-244