DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Beta-secretase 1
Ligand Name
N-{3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl}-5-methoxypyrazine-2-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VQSRKMNBWMHJKY-YTEVENLXSA-N
SMILES
COc1cnc(cn1)C(=O)Nc2ccc(c(c2)C34CN(CC3CSC(=N4)N)c5ncc(cn5)F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 7MYU
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Color Legend
Unassigned regionsLigand / hetero atomse7myuA1e7myuA2e7myuB1e7myuB2
ECOD domains from experimental PDB structures interacting with ligand ZR7
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P56817n/aZR77myue7myuA1A:184-385
P56817n/aZR77myue7myuA2A:-4-183
P56817n/aZR77myue7myuB1B:-3-183
P56817n/aZR77myue7myuB2B:184-385