FE3-S4 CLUSTER

P62623 — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -butenyl 4-diphosphate reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand F3S

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand F3S

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P62623	n/a	3f7t	F3S	A	999	e3f7tA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3f7t	F3S	A	999	e3f7tA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3f7t	F3S	A	999	e3f7tA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3f7t	F3S	B	999	e3f7tB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3f7t	F3S	B	999	e3f7tB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3f7t	F3S	B	999	e3f7tB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kef	F3S	A	997	e3kefA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kef	F3S	A	997	e3kefA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kef	F3S	A	997	e3kefA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kef	F3S	B	997	e3kefB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kef	F3S	B	997	e3kefB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kef	F3S	B	997	e3kefB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kel	F3S	A	997	e3kelA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kel	F3S	A	997	e3kelA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kel	F3S	A	997	e3kelA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kel	F3S	B	997	e3kelB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kel	F3S	B	997	e3kelB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kel	F3S	B	997	e3kelB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kem	F3S	A	997	e3kemA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kem	F3S	A	997	e3kemA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kem	F3S	A	997	e3kemA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kem	F3S	B	997	e3kemB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kem	F3S	B	997	e3kemB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3kem	F3S	B	997	e3kemB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3szu	F3S	A	997	e3szuA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3szu	F3S	A	997	e3szuA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3szu	F3S	A	997	e3szuA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3szu	F3S	B	997	e3szuB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3szu	F3S	B	997	e3szuB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3szu	F3S	B	997	e3szuB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0f	F3S	A	317	e3t0fA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0f	F3S	A	317	e3t0fA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0f	F3S	A	317	e3t0fA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0f	F3S	B	317	e3t0fB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0f	F3S	B	317	e3t0fB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0f	F3S	B	317	e3t0fB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0g	F3S	A	997	e3t0gA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0g	F3S	A	997	e3t0gA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0g	F3S	A	997	e3t0gA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0g	F3S	B	997	e3t0gB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0g	F3S	B	997	e3t0gB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3t0g	F3S	B	997	e3t0gB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3utd	F3S	A	317	e3utdA1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3utd	F3S	A	317	e3utdA2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3utd	F3S	A	317	e3utdA3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3utd	F3S	B	317	e3utdB1	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3utd	F3S	B	317	e3utdB2	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB
P62623	n/a	3utd	F3S	B	317	e3utdB3	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NadA-like/4-hydroxy-3-methylbut-2-enyl diphosphate reductase	LYTB