DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
Eukaryotic translation initiation factor 4E
Ligand Name
[[[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-selanyl-phosphoryl] [(2~{R},3~{S},4~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
LVNVABJMRYMPGM-DCILJVRDSA-O
SMILES
C[n+]1cn(c2c1c(nc(n2)N)O)C3C(C(C(O3)COP(=O)(O)OP(=O)(OP(=O)(O)OCC4C(C(C(O4)n5cnc6c5N=C(NC6=O)N)O)O)[SeH])O)OC
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5M7Z
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Color Legend
Unassigned regionsLigand / hetero atomse5m7zA1e5m7zB1e5m7zC1e5m7zD1
ECOD domains from experimental PDB structures interacting with ligand 7LO
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P63073n/a7LO5m7ze5m7zA1A:31-217
P63073n/a7LO5m7ze5m7zB1B:32-217
P63073n/a7LO5m7ze5m7zC1C:32-191