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(1R,2R)-N-[(2S,3S)-2-azanyl-3-methyl-pentyl]-N-[4-(4-propylphenyl)phenyl]-2-pyridin-2-yl-cyclopropane-1-carboxamide

P63096 — Guanine nucleotide-binding protein G subunit alpha-1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand J5F

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
P63096NoneJ5F000053293135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
P63096NoneJ5F000053296135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
Show other predicted domains (67)
PDB IDDomain NameECOD IDX GroupH GroupT GroupF Group
1KJYe1kjyA1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e1kjyC1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e1kjyC22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e1kjyA22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
1Y3Ae1y3aD1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e1y3aB1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e1y3aA1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e1y3aC22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e1y3aD22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e1y3aB22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e1y3aA22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
2G83e2g83A1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2g83B22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e2g83A22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
2GTPe2gtpA1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2gtpB1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2gtpB22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e2gtpA22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
2IK8e2ik8A1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2ik8C1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2ik8C22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e2ik8A22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
2OM2e2om2A1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2om2C1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2om2A22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e2om2C22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
2XNSe2xnsA1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2xnsB1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e2xnsA22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e2xnsB22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
3ONWe3onwA1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3onwB1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3onwA22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e3onwB22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
3QE0e3qe0A1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3qe0C4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3qe0B4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3qe0A22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e3qe0C32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e3qe0B32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
3QI2e3qi2A1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3qi2B4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3qi2A22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e3qi2B32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
3UMRe3umrA4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3umrA32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
3UMSe3umsA4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e3umsA32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
4G5Qe4g5qA1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e4g5qB4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e4g5qC4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e4g5qD4135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e4g5qA22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e4g5qB32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e4g5qC32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e4g5qD32004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
5JS7e5js7A2135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e5js7A12004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
5JS8e5js8A2135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e5js8A12004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
5TDHe5tdhA2135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e5tdhH2135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e5tdhA12004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
e5tdhH12004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
6CRKe6crkA1135.1.1Transducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainTransducin (alpha subunit), insertion domainG-alpha
e6crkA22004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA
6N4Be6n4bA12004.1.1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesAAA

ECOD domains from experimental PDB structures interacting with ligand J5F

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P63096n/a7ejxJ5FR401e7ejxA1P-loop domains-likeP-loop domains-relatedP-loop containing nucleoside triphosphate hydrolasesG-alpha