DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
DNA topoisomerase 4 subunit A
Ligand Name
3-amino-7-{(3R)-3-[(1S)-1-aminoethyl]pyrrolidin-1-yl}-1-cyclopropyl-6-fluoro-8-methylquinazoline-2,4(1H,3H)-dione
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SMONLCFJGCJROJ-WDEREUQCSA-N
SMILES
Cc1c2c(cc(c1N3CCC(C3)C(C)N)F)C(=O)N(C(=O)N2C4CC4)N
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 3LTN
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Color Legend
Unassigned regionsLigand / hetero atomse3ltnA4e3ltnA5e3ltnA6e3ltnB4e3ltnB5e3ltnB6e3ltnC1e3ltnC2e3ltnD1e3ltnD2
ECOD domains from experimental PDB structures interacting with ligand PDQ
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
P72525n/aPDQ3ltne3ltnA5A:3-156
P72525n/aPDQ3ltne3ltnB5B:3-156
P72525n/aPDQ3rafe3rafA5A:3-156
P72525n/aPDQ3rafe3rafB5B:3-156