4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3 -ium-2-yl]-4-oxidanyl-butanoic acid

P9WK11 — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TOG

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TOG

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P9WK11	n/a	5ess	TOG	C	601	e5essB2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	5ess	TOG	C	601	e5essC2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	5ess	TOG	C	601	e5essC4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M_2
P9WK11	n/a	5ess	TOG	D	601	e5essA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	5ess	TOG	D	601	e5essA3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	5ess	TOG	D	601	e5essD2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	6o0g	TOG	C	601	e6o0gB1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	6o0g	TOG	C	601	e6o0gC1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M_2
P9WK11	n/a	6o0g	TOG	C	601	e6o0gC2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	6o0g	TOG	D	601	e6o0gA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	6o0g	TOG	D	601	e6o0gA3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	6o0g	TOG	D	601	e6o0gD1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	6o0g	TOG	D	601	e6o0gD3	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M_2