(1~{R},2~{S},5~{S},6~{S})-2-[(1~{S})-1-[3-[(4-azanylidene-2-methyl-1~{H}-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl (phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1,4-bis(oxidanyl)-4-oxidanylidene-butyl]-6-oxidanyl-5-(3-oxid anyl-3-oxidanylidene-prop-1-en-2-yl)oxy-cyclohex-3-ene-1-carboxylic acid

P9WK11 — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TOI

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TOI

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P9WK11	n/a	5esu	TOI	C	601	e5esuB1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	5esu	TOI	C	601	e5esuC3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	5esu	TOI	C	601	e5esuC4	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M_2
P9WK11	n/a	5esu	TOI	D	602	e5esuA2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	5esu	TOI	D	602	e5esuA3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	5esu	TOI	D	602	e5esuD2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	5esu	TOI	D	602	e5esuD3	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M_2
P9WK11	n/a	6o04	TOI	C	601	e6o04B3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	6o04	TOI	C	601	e6o04C1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	6o04	TOI	C	601	e6o04C2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M_2
P9WK11	n/a	6o04	TOI	D	602	e6o04A2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P9WK11	n/a	6o04	TOI	D	602	e6o04A3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P9WK11	n/a	6o04	TOI	D	602	e6o04D1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M_2
P9WK11	n/a	6o04	TOI	D	602	e6o04D3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C